Depression: A major mental disorder in the 21st Century

Depression or Major Depressive Disorder in medical terms is a disorder which is gaining ground around the world with increasing pressure to do well. It is also known as major depression, clinical depression, unipolar depression; and in the case of bouts of depression at regular intervals, recurrent depression. It is characterized by a constantly low mood, feelings of low self-esteem, sadness and a lack of interest in enjoyable activities, leading to a loss in productivity. There are many procedures and medications to treat depression but like all mental disorders, people are not completely satisfied with the results.

How to tackle depression:

Depression research study is going on in various fields, and it is the need of the hour as it will help doctors understand the disorder better and treat it with greater versatility. The various types of depression research study are:

  • Effect of sustained doses of ketamine on depression, with neuroimaging

This study is being done with the purpose of evaluating the rapid and long-lasting antidepressant effects of regular doses of ketamine on the patient’s brain. Doctors aim to learn how it affects the areas of the brain important for the regulation of mood and if there are certain unique signatures which could aid doctors in predicting subjective response of the drug. It also helps in determining whether such regular doses of ketamine are effective and safe in treating depression symptoms.

  • Effects of TMS and Psychotherapy on the Brain Function of a depressed person

This particular depression research study asks its participants suffering from depression to test the combined effects of psychotherapy and repetitive transcranial magnetic stimulation (TMS) on the brain function of the individuals.

  • The brain changes of a depressed person under fear or anxiety

The main purpose of this research study is to monitor the participants and improve the understanding of how their body and brain operate when they feel afraid or anxious.